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心塞 can be translated to English as "frustration" or "anxiety". It comes from the Chinese characters 心 (xīn) meaning "heart" and 塞 (sāi) meaning "to plug up or block".
Here are some example sentences in English and their translations in Chinese:
I felt a sense of frustration when I couldn't find my keys. (我在找不到我的钥匙时感到了心塞。)
The long line at the grocery store gave me anxiety. (在杂货店里排长队让我心塞。)
The traffic jam on the highway made me feel frustrated. (高速公路上的交通堵塞让我感到心塞。)